Author

Weibo Zhao

Zhejiang UniversityORCID 0000-0001-5029-6047Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:contrastive learning· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Odin ZhangiD· 2 shared Yuntao YuiD· 2 shared Chang‐Yu HsiehiD· 1 shared Chenqing HuaiD· 1 shared Dong Ming GuoiD· 1 shared Gang Du· 1 shared Haitao LiniD· 1 shared Haiyang ZhongiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBioinformatics

Odin ZhangORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintAug 21, 2026

NACraft: Programmatic nucleic-acid aptamer design via all-atom structure-model feedback

Heqin Zhu, Jiaqi Wang, Weibo Zhao…·Odin Zhang

NACraft generates high-confidence nucleic-acid aptamers for diverse protein targets using a programmatic framework with structure-model feedback, outperforming existing methods in several evaluations.

DOI 10.64898/2026.08.15.744087

DNA methylationproteomics

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BioinformaticsNature Computational SciencePeer-reviewedOct 15, 2025

ECloudGen: Leveraging Electron Clouds as a Latent Variable to Scale Up Structure-based Molecular Design

Odin Zhang, Jieyu Jin, Zhenxing Wu…·Tingjun Hou

ECloudGen improves molecular design by using electron clouds as latent variables, generating more potent binders and exploring broader chemical space than existing methods.

9 citations

deep learningcontrastive learning

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