Jiaqi Wang

RFOptimization improves all-atom biomolecular binder design by combining gradient-guided sequence optimization with orthogonal predictors to enhance in silico success rates.

NACraft generates high-confidence nucleic-acid aptamers for diverse protein targets using a programmatic framework with structure-model feedback, outperforming existing methods in several evaluations.

This paper introduces CellVS-Net, a cell-level virtual screening model that outperforms existing methods on two benchmarks, demonstrating its viability as an alternative to molecular-level drug screening.