Author

Richard J. Gildea

Diamond Light SourceORCID 0000-0001-5038-6958Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Assay:proteomics· 1

Frequent Co-Authors

Aleksandr KovaltsukiD· 1 shared Callum D. OweniD· 1 shared Charlotte Mary DeaneiD· 1 shared Claire M. Strain-DamerelliD· 1 shared Claire MarksiD· 1 shared Constantin SchneideriD· 1 shared Daniel Allen NissleyiD· 1 shared Daniel CuttingiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioinformatics

Aleksandr KovaltsukORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintOct 3, 2024

Computational design of developable therapeutic antibodies: efficient traversal of binder landscapes and rescue of escape mutations

Frédéric A. Dreyer, Constantin Schneider, Aleksandr Kovaltsuk…·Charlotte Mary Deane

This paper presents a computational pipeline for designing therapeutic antibodies using AI and physics-based methods, showing improved binding and developability across SARS-CoV-2 variants.

3 citations

proteomicsmachine learning (classical)

𝕏 PostBluesky

Molecular BiologyActa Crystallographica Section D Structural BiologyPeer-reviewedMay 18, 2022

xia2.multiplex: a multi-crystal data analysis pipeline

Richard J. Gildea, James Beilsten‐Edmands, Danny Axford…·Graeme Winter

xia2.multiplex merges multi-crystal data sets in macromolecular crystallography to improve data quality and facilitate analysis.

79 citationstop 3%

experimental assay

𝕏 PostBluesky