Paweł Nałęcz‐Jawecki

The paper quantifies how cancer and drug treatments affect the information capacity of RTK signaling pathways using optogenetic stimulation and information theory.

The paper uses a numerical model to study information transmission in cell monolayers, identifying stochastic factors that affect wave propagation and determining optimal channel widths and wave frequencies for effective communication.

The paper demonstrates that non-identifiable models can still have predictive power when measured with appropriate stimulation protocols and iterative variable measurements.

The paper quantifies the information transmission rate of the MAPK/ERK pathway, finding it can transmit at least 6 bits per hour.