Author

Paolo Armando Gagliardi

University of BernORCID 0000-0002-4818-035XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2 Bioinformatics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 2 Approach:deep learning· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:trajectory inference· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Olivier C. PertziD· 4 shared Benjamin GrädeliD· 2 shared Coralie DessaugesiD· 2 shared Lucien HinderlingiD· 2 shared Maciej DobrzyńskiiD· 2 shared Agne FrismantieneiD· 1 shared Alain PulferiD· 1 shared Alessandro GiustiiD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersSystems Biology

Olivier C. PertzORCID

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4 papers

Recent·Most cited

Tracking Coordinated Cellular Dynamics in Time-Lapse Microscopy with ARCOS.px

Benjamin Grädel, Lea Brönnimann, Paolo Armando Gagliardi, Lucien Hinderling, Olivier C. Pertz, Maciej Dobrzyński

ARCOS.px tracks spatial clusters in time-lapse microscopy to study dynamic cellular structures and their interactions.

Journal of Cell Science · Nov 3, 2025Peer-reviewedCell Biology

Transformer-based spatial-temporal detection of apoptotic cell death in live-cell imaging.

Alain Pulfer, Diego Ulisse Pizzagalli, Paolo Armando Gagliardi, Lucien Hinderling, Paul G. Lopez, Romaniya Zayats, Pau Carrillo-Barberà, Paola Antonello, Miguel Palomino‐Segura, Benjamin Grädel, Mariaclaudia Nicolai, Alessandro Giusti, Marcus Thelen, Luca Maria Gambardella, Thomas T. Murooka, , Santiago González

This paper introduces ADeS, a deep learning system for detecting apoptosis in live-cell imaging with high accuracy and robustness across diverse conditions.

eLife · Sep 28, 2023Peer-reviewedBioinformatics

The MAPK/ERK channel capacity exceeds 6 bit/hour

Paweł Nałęcz‐Jawecki, Paolo Armando Gagliardi, Marek Kochańczyk, Coralie Dessauges, Olivier C. Pertz, Tomasz Lipniacki

The paper quantifies the information transmission rate of the MAPK/ERK pathway, finding it can transmit at least 6 bits per hour.

PLoS Computational Biology · May 22, 2023Peer-reviewedSystems Biology

Optogenetic actuator/ERK biosensor circuits identify MAPK network nodes that shape ERK dynamics

Coralie Dessauges, Jan Mikelson, Maciej Dobrzyński, Marc‐Antoine Jacques, Agne Frismantiene, Paolo Armando Gagliardi, Mustafa Khammash, Olivier C. Pertz

The paper uses optogenetic actuator and ERK biosensor circuits to study MAPK network dynamics and identifies RSK2-mediated feedback as critical for ERK regulation and drug response.

Molecular Systems Biology · Jun 1, 2022Peer-reviewedSystems Biology