Joshua S. Kaminker

scEPS integrates GWAS and single-cell data to identify disease-associated cell neighborhoods by testing gene expression variance explained in disease contexts.

The paper constructs an integrated atlas of astrocytes from human and mouse neurodegenerative disease models, identifying conserved and divergent subtypes across species.

This study identifies Tmc3-expressing vagal ganglion neurons that regulate broncho-constriction and dilation, impacting respiratory function and offering potential therapeutic targets for respiratory diseases.

The paper introduces SCimilarity, a metric learning framework for querying and comparing single-cell RNA-seq data across the human body, revealing commonalities in fibrosis-associated macrophages.

The paper creates a cross-species transcriptomic atlas of dorsal root ganglia to identify conserved and species-specific gene expression programs related to sensory function.