Daryle J. DePianto

This study shows that blocking OSM and IL-6 reduces fibrosis and inflammation in pulmonary fibrosis by targeting their shared receptor and distinct pathways.

The paper introduces SCimilarity, a metric learning framework for querying and comparing single-cell RNA-seq data across the human body, revealing commonalities in fibrosis-associated macrophages.

The paper identifies molecular and structural changes in aging human lungs that contribute to fibrosis and impair lung function.