Author

James Maksymetz

GenentechORCID 0000-0002-0486-1153Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

David H. HackosiD· 2 shared Aaron D. GitleriD· 1 shared Aaron M. BenderiD· 1 shared Amanda R. Jacobson· 1 shared Anita Hermann· 1 shared Catherine A. DoyleiD· 1 shared Christoph SchweingruberiD· 1 shared Colleen Marie NiswenderiD· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersNeuroscience

David H. HackosORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Human motor neurons are rare and can be transcriptomically divided into known subtypes

Olivia Gautier, Jacob A. Blum, James Maksymetz, Derek C. Chen, Christoph Schweingruber, Irene Mei, Anita Hermann, David H. Hackos, Eva Hedlund, John Ravits, Aaron D. Gitler

The paper analyzes single-nucleus RNA-seq data from human spinal cord neurons, identifies motor neurons as rare, and highlights discrepancies with a prior study due to potential misclassification of cholinergic debris.

Neuron · Dec 1, 2023Peer-reviewedNeuroscience

High-resolution cross-species transcriptomic atlas of dorsal root ganglia reveals species-specific programs for sensory function

Min Jung, Michelle Dourado, James Maksymetz, Amanda R. Jacobson, Miriam Baca, Oded Foreman, David H. Hackos, Lorena Riol‐Blanco, Joshua S. Kaminker

The paper creates a cross-species transcriptomic atlas of dorsal root ganglia to identify conserved and species-specific gene expression programs related to sensory function.

bioRxiv · Jun 21, 2022 · PreprintNeuroscience

Biased M1 positive allosteric modulators reveal novel role of phospholipase D in M1-dependent rodent cortical plasticity

Sean P. Moran, Zixiu Xiang, Catherine A. Doyle, James Maksymetz, Xiaohui Lv, Sehr Faltin, Nicole M. Fisher, Aaron M. Bender, Colleen Marie Niswender, Jerri M. Rook, Craig W. Lindsley, Peter Jeffrey Conn

The paper shows that phospholipase D is essential for M1 PAM-induced long-term depression in rodent prefrontal cortex, and biased M1 PAMs that do not activate PLD have distinct effects on cortical plasticity.

Science Signaling · Dec 3, 2019Peer-reviewedNeuroscience