NeurosciencebioRxivPreprint
State-specific inhibition of NMDA receptors by memantine depends on intracellular calcium and provides insights into NMDAR channel blocker tolerability
Matthew B. Phillips, Nadya V. Povysheva, Karen A. Hartnett…·Jon W. Johnson
This study shows memantine inhibits NMDA receptors more effectively under high intracellular Ca2+ conditions, offering insights into its tolerability compared to other NMDAR blockers.