Misaki Kinoshita

This paper designs a cyclic peptide ligand using AlphaFold2 for specific purification of human complement C1q from plasma, demonstrating high selectivity and mild elution conditions.

This study develops a chemical method to enhance oxidative protein folding within PDIA6 condensates, showing up to 12-fold acceleration in vitro and improved insulin secretion in cells.

The paper introduces a methodology to generate cyclic peptide libraries with uniform coverage of physicochemical properties using a protein language model and cyclic permutation averaging.