Nikita Soni

This study uses optogenetics to model C9orf72 poly-PR condensation in cells, revealing anisotropic nuclear condensates that cause TDP-43 pathology without stress response activation.

This study identifies a novel RNA-binding function of PGC-1alpha that couples transcriptional co-activation with mRNA nuclear export and mitochondrial homeostasis.

This paper identifies GLT8D1 mutations as a cause of ALS by disrupting neurotrophin signaling in lipid rafts through reduced ganglioside expression.