Author

Aytaç Gül

University of SheffieldORCID 0009-0003-6353-9505Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

Guillaume M. HautbergueiD· 2 shared Lydia M. CastelliiD· 2 shared Ya-Hui LiniD· 2 shared Adrian Higginbottom· 1 shared Alexander J. WhitworthiD· 1 shared Álvaro Sánchez-MartíneziD· 1 shared Ambrosius P. SnijdersiD· 1 shared Amy Walton· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMolecular Biology

Guillaume M. HautbergueORCID

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2 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedSep 7, 2023

The master energy homeostasis regulator PGC-1alpha couples transcriptional co-activation and mRNA nuclear export

Simeon R. Mihaylov, Lydia M. Castelli, Ya-Hui Lin…·Guillaume M. Hautbergue

This study identifies a novel RNA-binding function of PGC-1alpha that couples transcriptional co-activation with mRNA nuclear export and mitochondrial homeostasis.

64 citationstop 2%

humanproteomics

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Molecular BiologyScience Translational MedicinePeer-reviewedMar 1, 2023

A cell-penetrant peptide blocking C9ORF72-repeat RNA nuclear export suppresses neurodegeneration

Lydia M. Castelli, Ya-Hui Lin, Álvaro Sánchez-Martínez…·Guillaume M. Hautbergue

This paper develops a cell-penetrant peptide that blocks C9ORF72-repeat RNA nuclear export, reducing neurodegeneration in preclinical models of ALS and FTD.

16 citations

humanDrosophila

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