BiophysicsJournal of Medicinal ChemistryPeer-reviewed
Key role of P230 in the hinge region on the IgG architecture and function
Yuuki Koseki, Yuki Yamaguchi, Michihiko Aoyama…·José M. M. Caaveiro
This study investigates the role of Pro230 in the hinge region of IgG by deleting it, revealing structural changes and functional effects on FcγRI-mediated activity.