Yi-Hsuan Pan

The paper identifies accelerated evolution of lung-related genes in vertebrate lineages surviving end-Permian and end-Triassic mass extinctions, suggesting adaptation to hypoxia.

The paper uses computational modeling and fossil evidence to show a severe population bottleneck in ancient Homo around 930,000 years ago, linked to hominin dispersals and brain size increase.

This study shows that Lactiplantibacillus plantarum PS128 improves autism-like behaviors in Fmr1 knockout mice by restoring gut microbiota-driven polyamine homeostasis.

This study identifies a conserved interaction between CPS1 and AGMAT in torpid bats, maintaining urea cycle function during torpor.

This study shows that sociability and social hierarchy are genetically separable in amniotes through PAS1 mutations in mice and wallabies/chickens.

This study identifies a non-image-forming visual circuit in mice that mediates innate fear of heights, independent of primary visual cortex processing.

The paper shows that an ASD-linked mutation in Katnal2 impairs ependymal ciliary motion, causing hydrocephalus and behavioral deficits in mice.

This study estimates human recombination rates using the UK10K dataset and shows that larger sample sizes reduce recombination rate fluctuations and improve precision.

The paper introduces Coronavirus GenBrowser (CGB), a tool for analyzing and visualizing SARS-CoV-2 genomic sequences to study transmission and evolution.

This study identifies CDH11 as an ASD-associated gene using matched-gene co-expression analysis and behavioral validation in mice.