Yi Zhou

PA-SfM: Tracker-free freehand 3D photoacoustic imaging via differentiable acoustic radiation

PA-SfM enables tracker-free freehand 3D photoacoustic imaging with improved spatial coverage and reconstruction quality compared to traditional methods.

Targeting NAT10 suppresses TFH responses and alleviates allergic asthma via an ac4C-TOX2 axis

This study identifies NAT10 as a regulator of TFH cell differentiation through the acC-TOX2 axis, showing that targeting NAT10 suppresses allergic asthma in mice.

Assembly of the ATP-driven cobalt chelatase

The paper investigates the step-wise assembly mechanism of the ATP-driven cobalt chelatase CobSTN involved in vitamin B12 biosynthesis.

Severe bottleneck of ancient Homo populations: Insights from computational modeling and fossil evidence

The paper uses computational modeling and fossil evidence to show a severe population bottleneck in ancient Homo around 930,000 years ago, linked to hominin dispersals and brain size increase.

Translation sustains productive Pol II elongation through maintenance of nuclear RNA surveillance

This study shows that ongoing translation sustains productive Pol II elongation and nuclear RNA homeostasis in mouse embryonic stem cells by maintaining RNA surveillance.

Functional orthogonality of WRN inhibitor resistance enables alternating therapy and mutation-tolerant inhibitor design in MSI-H cancers

This study shows that resistance to different WRN inhibitors in MSI-H cancers creates orthogonal vulnerabilities, enabling alternating therapy and mutation-tolerant inhibitor design.

Temporal boundary gating of auditory sensitivity

The paper shows that auditory sensitivity to sound changes is gated by temporal boundaries, with sensitivity peaking mid-sound and dropping near onset and offset.