NeurosciencebioRxivPreprint
Fmr1 KO causes delayed rebound spike timing in mediodorsal thalamocortical neurons through regulation of HCN channel activity
Gregory J. Ordemann, Polina N. Lyuboslavsky, Alena Kizimenko, Audrey C. Brumback
This study shows that Fmr1 knockout in mice reduces HCN channel activity in mediodorsal thalamocortical neurons, leading to delayed rebound spike timing and potential disruptions in thalamocortical circuitry.
DOI 10.1101/2025.02.02.636122