Author

Melissa Klug

TUM KlinikumORCID 0000-0001-5193-2770Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:CITE-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Dario BongiovanniiD· 2 shared Jan BaumbachiD· 2 shared Markus ListiD· 2 shared Amit M. FenniD· 1 shared Chit Tong LioiD· 1 shared Judith BernettiD· 1 shared Lis ArendiD· 1 shared Maria L. ElkjaeriD· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBioinformatics

Dario BongiovanniORCID

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2 papers

Recent·Most cited

BioinformaticsGenome biologyPeer-reviewedDec 1, 2021

Functional enrichment of alternative splicing events with NEASE reveals insights into tissue identity and diseases

Zakaria Louadi, Maria L. Elkjaer, Melissa Klug…·Olga V. Tsoy

The paper introduces NEASE, a tool for functional analysis of alternative splicing events, showing its ability to identify pathways related to tissue identity and cell type development, and highlight splicing-related biomarkers.

37 citations

statistical modelgene regulatory network inference

𝕏 PostBluesky

BioinformaticsBriefings in BioinformaticsPeer-reviewedOct 16, 2021

A Systematic Comparison of Differential Analysis Methods for CyTOF Data

Lis Arend, Judith Bernett, Quirin Manz…·Markus List

The paper compares differential expression analysis methods for CyTOF data, finding that median-based methods are reliable for non-zero-inflated data while methods using full distributions handle zero-inflation better but may overpredict.

18 citations

CITE-seqbulk RNA-seq

𝕏 PostBluesky