Chit Tong Lio

The paper benchmarks differential transcript usage analysis tools across static and dynamic conditions, finding optimal tools for different data types and experimental settings.

This paper refines the Tangram spatial mapping tool to improve consistency and reliability in mapping single-cell RNA-seq data to spatial transcriptomics data.

The paper investigates alternative splicing in mechanically stretched podocytes, identifying splicing events in Shroom3 and Myl6 that may contribute to hypertensive nephropathy.

Spycone analyzes alternative splicing in time course data to detect isoform switches and provides downstream analysis tools.

DICAST benchmarks alternative splicing analysis tools, showing STAR and HISAT2 perform best, and proposes a reporting standard for event detection.

The paper introduces NEASE, a tool for functional analysis of alternative splicing events, showing its ability to identify pathways related to tissue identity and cell type development, and highlight splicing-related biomarkers.