Author

Sadikshya Rijal

Arizona State UniversityORCID 0000-0001-5213-7883Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2

Frequent Co-Authors

Xiao‐Jun TianiD· 2 shared Abdelrahaman Youssef· 1 shared Abdelrahman Youssef· 1 shared Austin Stone· 1 shared Kylie Standage-BeieriD· 1 shared Rixin Zhang· 1 shared Rong ZhangiD· 1 shared Rong Zhang· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersSynthetic Biology

Xiao‐Jun TianORCID

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2 papers

Recent·Most cited

Synthetic BiologyACS Synthetic BiologyPeer-reviewedSep 10, 2025

CRISPRi-Linked Multi-Module Negative Feedback Loops to Address Winner-Take-All Resource Competition

Sadikshya Rijal, Kylie Standage-Beier, Rong Zhang…·Xiao‐Jun Tian

This study introduces a CRISPRi-based controller to mitigate Winner-Take-All behavior in synthetic gene circuits by promoting balanced module activation through negative feedback.

4 citations

experimental assay

𝕏 PostBluesky

Synthetic BiologybioRxivPreprintNov 1, 2024

Phase Separation to Resolve Growth-Related Circuit Failures

Rong Zhang, Wenqi Yang, Rixin Zhang…·Xiao‐Jun Tian

This paper introduces a method using liquid-liquid phase separation to stabilize synthetic gene circuits against growth fluctuations by maintaining local transcription factor concentration.

5 citations

experimental assay

𝕏 PostBluesky