Rong Zhang

LCN2+ Astrocytes Mark a Pro-inflammatory Astrocyte State Associated with Secondary Brain Injury After Cerebral Venous Thrombosis

A virus co-opts vector's m⁶A machinery for adaptive compensation

The paper shows TYLCV co-opts its vector's m6A machinery to enhance reproductive fitness in resistant whiteflies, revealing a mechanism for adaptive virus-vector interactions.

A horizontally transferred fungal deubiquitinase facilitates insecticides resistance in whitefly

This study identifies a horizontally transferred fungal deubiquitinase, BtUCH19, that enhances insecticide resistance in whiteflies by stabilizing a detoxification enzyme through ubiquitin modification.

CTLA-4 inhibitors drive colitis through metabolic reprogramming-mediated Treg/Th17 imbalance

This study identifies metabolic reprogramming as a mechanism by which CTLA-4 inhibitors cause colitis, showing that metformin can alleviate this toxicity without affecting antitumor efficacy.

Haemagglutinin 162-164 deletions enhance influenza B/Victoria virus fitness and virulence in vivo

This study shows that HA deletions and substitutions in influenza B/Victoria viruses enhance replication and virulence, contributing to their evolutionary success and vaccine challenges.

Phase Separation to Resolve Growth-Related Circuit Failures

This paper introduces a method using liquid-liquid phase separation to stabilize synthetic gene circuits against growth fluctuations by maintaining local transcription factor concentration.

Transcutaneous auricular vagus nerve stimulation increases eye-gaze on salient facial features and oxytocin release

Changeover from signalling to energy-provisioning lipids during transition from colostrum to mature milk in the giant panda (Ailuropoda melanoleuca)

The paper examines lipid transitions in giant panda milk from colostrum to mature milk, finding an early provision of signaling lipids followed by a shift to energy-provisioning lipids.

Changes in the milk metabolome of the giant panda (Ailuropoda melanoleuca) with time after birth: Three phases in early lactation and progressive individual differences

This study analyzes changes in the milk metabolome of giant pandas over early lactation, identifying three phases and individual differences, with implications for neonatal development.