Author

Balaji Santhanam

Columbia UniversityORCID 0000-0001-5248-309XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Călin C. GuetiD· 1 shared Claire Fourcade· 1 shared Claudia IgleriD· 1 shared Florian M. PauleriD· 1 shared Gašper TkačikiD· 1 shared Torsten WaldminghausiD· 1 shared

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2021-2021 · peak 1/yr

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1 shared paperMolecular Biology

Călin C. GuetORCID

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintOct 20, 2021

Limited specificity of molecular interactions incurs an environment-dependent fitness cost in bacteria

Claudia Igler, Claire Fourcade, Torsten Waldminghaus…·Călin C. Guet

The paper shows that non-specific TF-DNA binding in bacteria reduces population growth across environments due to low specificity, TF cooperativity, and TF-to-DNA ratios.

2 citations

bacteria (other)DNA methylation

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