Molecular BiologybioRxivPreprint
Interaction of modified oligonucleotides with nuclear proteins, formation of novel nuclear structures and sequence-independent effects on RNA processing
Loren L. Flynn, Ruohan Li, May Thandar Aung-Htut…·Sue Fletcher
This study investigates how modified oligonucleotides affect nuclear structures and RNA processing, finding that phosphorothioate backbones cause subnuclear disruptions and RNA processing changes.
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