Author

Jim E. Horne

University of CambridgeORCID 0000-0001-5260-2634Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:E. coli· 1 Research Focus:protein design· 1 Assay:protein structure· 1

Frequent Co-Authors

Alex KangiD· 1 shared Alyssa Q. StivingiD· 1 shared Anastassia Andreevna VorobievaiD· 1 shared Andrzej HarrisiD· 1 shared Ashraf ZarkaniD· 1 shared Asim K. BeraiD· 1 shared Ben F. LuisiiD· 1 shared Ben HS JiniD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperSynthetic Biology

Alex KangORCID

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2 papers

Recent·Most cited

Molecular BiologyeLifePeer-reviewedApr 15, 2026

A lipoprotein partner for the Escherichia coli outer membrane protein TolC

Jim E. Horne, Elise Kaplan, Ben HS Jin…·Ben F. Luisi

The paper identifies YbjP as a lipoprotein partner for E. coli TolC, showing its interaction with TolC's periplasmic surface and N-terminal lipid moiety, and presents cryo-EM structures of related efflux pump complexes.

1 citation

E. coliexperimental assay

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Synthetic BiologySciencePeer-reviewedFeb 19, 2021

De novo design of transmembrane beta-barrels

Anastassia Andreevna Vorobieva, Paul C. White, Binyong Liang…·David A. Baker

This study successfully designs transmembrane beta-barrels from first principles, revealing structural constraints and enabling custom pore design for biotechnology applications.

153 citationstop 1%

protein structureexperimental assay

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