Alyssa Q. Stiving

This paper develops an antibody-free mass spectrometry method to assess mRNA vaccine functionality and translation fidelity using cell-free translation and LC-MS.

This study optimizes an activity-based protein profiling workflow to detect polysorbate-degradative enzymes at 10 ppb in biotherapeutic samples.

The paper evaluates diaPASEF for HCP analysis in biopharmaceutical processes, showing improved quantification and throughput compared to standard methods.

This study successfully designs transmembrane beta-barrels from first principles, revealing structural constraints and enabling custom pore design for biotechnology applications.