Author

Hao Wang

Harbin Medical UniversityORCID 0000-0001-5279-3645Unclaimed ORCID profile · follow to get notified of new preprints

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Hao Wang13 papers · Altius Institute for Biomedical Sciences

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1

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Bin SuniD· 1 shared Manjie ZhangiD· 1 shared Wenjian Li· 1 shared Xiaohui CheniD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperBiophysics

Bin SunORCID

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1 paper

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BiophysicsbioRxivPreprintOct 28, 2025

The disordered JM motif in RTKs promotes classical DFGout conformation formation via dynamic effect

Xiaohui Chen, Hao Wang, Wenjian Li…·Bin Sun

This study shows that the disordered JM motif in RTKs dynamically influences DFGout conformation formation, promoting classical conformations favorable for inhibitor binding.

DOI 10.1101/2025.10.28.684995

humanstructural biology

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