Luisa Castagnoli

The paper curates causal gene-protein interactions linked to autism and develops tools to explore their functional relationships with phenotypes and pathways.

Myo-REG integrates and curates molecular interactions and signaling pathways involved in muscle regeneration, providing a web portal for exploring cell-cell and intracellular interactions.

The paper presents a large-scale cancer pharmacogenomic screen with 11,576 experiments on 910 drug combinations across 85 cancer cell lines, enabling crowd-sourced prediction of synergistic drug pairs and biomarkers.

This study uses single-cell mass cytometry to analyze skeletal muscle cell dynamics during regeneration and ageing, revealing population heterogeneity and responses to perturbations.

This study shows that NOTCH signaling inhibits adipogenesis in wild-type FAPs but not in mdx FAPs, with TNF-α restoring NOTCH sensitivity in mdx FAPs.