Alessandro Palma

This study identifies microglial subpopulations and gene signatures in neurodegenerative diseases using single-cell transcriptomics.

The paper shows that ribosome quality control via ZNF598 degradation helps aneuploid cells survive proteotoxic stress, with ZNF598 expression linked to tumor aneuploidy.

The paper creates a statistical genomics portrait of lncRNA genes for comparison with protein-coding genes to explore the non-coding genome.

This study identifies HSCHARME, a lncRNA altered in cardiomyopathies, which promotes cardiomyocyte differentiation through splicing regulation.

The paper identifies novel lncRNA-mediated networks dysregulated in ALS by analyzing single-nucleus RNA-seq data from human brain cortex.

The paper identifies critical nodes in the human protein-protein interaction network that have the greatest impact on network fragmentation and compares their biological relevance to essential genes.

Myo-REG integrates and curates molecular interactions and signaling pathways involved in muscle regeneration, providing a web portal for exploring cell-cell and intracellular interactions.