Luana Licata

The paper presents a manually curated dataset of protein binding domains, linking them to molecular interactions and genomic variations for benchmarking and disease mechanism studies.

BactMentha is a database of annotated bacteria-host protein interactions for human, mouse, and rat, including virulence proteins and predicted interaction interfaces.

The paper constructs a tissue-specific protein interaction atlas using proteomic data from 11 human tissues, identifying key drivers of inter-tissue variation and prioritizing disease genes in brain disorders.

The paper analyzes GPCR signaling dysregulation in cancer transcriptomics data to identify therapeutic targets and survival-associated signaling axes.

The paper curates causal gene-protein interactions linked to autism and develops tools to explore their functional relationships with phenotypes and pathways.

The paper analyzes microRNA interactions in three rare disorders to assess data availability and annotation consistency across databases.

The paper describes the development of a computational knowledge repository, the COVID-19 Disease Map, which curates SARS-CoV-2 virus-host interaction mechanisms and provides tools for their analysis and application.

The paper assesses the value and sustainability of ELIXIR Core Data Resources, showing their critical role in preserving biological data and highlighting funding challenges.

The paper curates a dataset of physical molecular interactions between SARS-CoV-2, SARS-CoV-1, and other Coronaviridae proteins, providing a resource for studying virus-host interactions.

Myo-REG integrates and curates molecular interactions and signaling pathways involved in muscle regeneration, providing a web portal for exploring cell-cell and intracellular interactions.

The paper introduces CausalTAB, an updated format for representing causal signaling interactions, enhancing the precision and coverage of signaling network modeling.

The paper presents a dataset of 28,000 annotations describing how amino acid mutations affect protein interactions, available through the IntAct website.