NeurosciencebioRxivPreprint
Cortical inhibitory parvalbumin interneurons exhibit metabolic specializations coordinated by PGC-1α that are lost in rodents and humans after traumatic brain injury
Sadi Quiñones, Jason C Wang, Elliot Kim…·Chris G. Dulla
The paper shows that PV-INs have unique metabolic specializations lost after TBI, which can be rescued by 2-deoxyglucose, and identifies PGC-1α and lncRNAs as key factors in this dysfunction.