Unveiling the double-edged sword: SOD1 trimers possess tissue-selective toxicity and bind septin-7 in motor neuron-like cells
Esther Sue Choi, Brianna Hnath, Congzhou Mike Sha, Nikolay V. Dokholyan
This paper identifies tissue-selective toxicity of SOD1 trimers and their interaction with septin-7 in motor neuron-like cells, revealing pathways linked to ALS pathophysiology.
Structure · Aug 28, 2024Peer-reviewedNeuroscience