Yoon-Mo Yang

The paper shows that the ubiquitin-proteasome system degrades Rps26 during high salt stress in yeast, enabling the formation of Rps26-deficient ribosomes and stress resistance.

The paper shows that chaperones repair oxidized ribosomes by releasing damaged ribosomal proteins and incorporating newly synthesized ones, revealing a novel mechanism for ribosome repair under oxidative stress.

The paper shows how the chaperone Tsr2 releases and recycles Rps26 from ribosomes during stress, enabling a reversible ribosome response without bypassing quality control.