DiffuChannel: A Conditional Denoising Diffusion Model that Synthesises Single-Molecule Patch-Clamp Data with Exactly Known Idealisation (Ground Truth)
Samuel A. Ball, Richard Barrett‐Jolley
DiffuChannel generates synthetic single-molecule patch-clamp data with known idealisation using a conditional diffusion model, outperforming GAN-based methods in stability and realism.
bioRxiv · Oct 14, 2026 · PreprintBiophysics