Author

Paolo Cremaschi

Human TechnopoleORCID 0000-0001-5349-4188Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:variant effect prediction· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Francesco IorioiD· 2 shared Riccardo Roberto De LuciaiD· 2 shared Umberto PerroniD· 2 shared Alessandro VanniniiD· 1 shared Alessandro VincetiiD· 1 shared Alessia Marinelli· 1 shared Alexandra LivanovaiD· 1 shared Andrea SottorivaiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersBioinformatics

Francesco IorioORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintSep 12, 2026

CRISPR-enhanced assessment of variants of unknown significance nominates oncology therapeutic targets and drug repositioning opportunities

Aurora Savino, Athanasios Oikonomou, Francesca Perrone…·Francesco Iorio

CRISPR-VUS identifies rare variants linked to gene dependency in cancer cell lines, prioritizing potential drivers and therapeutic targets through functional validation.

DOI 10.64898/2026.01.20.700565

humanwhole-exome sequencing

𝕏 PostBluesky

Cancer BiologybioRxivPreprintSep 7, 2026

The RNA cargo of plasma-derived extracellular vesicles in mCRPC patients captures cancer cells and tumor microenvironment signals

Federico Vannuccini, Yari Ciani, Vera Mugoni…·Francesca Demichelis

The paper profiles EV-RNA and cfDNA from mCRPC patients to identify prognostic biomarkers and tumor microenvironment signals.

DOI 10.64898/2026.09.03.747025

humanbulk RNA-seq

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BioinformaticsCell Reports MethodsPeer-reviewedJan 1, 2023

CRISPRcleanR WebApp: an interactive web application for processing genome-wide pooled CRISPR-Cas9 viability screen

Alessandro Vinceti, Riccardo Roberto De Lucia, Paolo Cremaschi…·Francesco Iorio

CRISPRcleanRWebApp is a web tool that processes CRISPR-Cas9 viability screens to reduce false positives by correcting biases in gene targeting.

11 citations

whole-genome sequencingstatistical model

𝕏 PostBluesky