Daniel R. Zerbino

This study shows that long-term culture of human intestinal organoids leads to DNA methylation changes, altered gene expression, and functional shifts, suggesting potential confounding effects in research.

The paper describes the Ensembl COVID-19 resource, which integrates SARS-CoV-2 genomic data and variant annotations to support research on virus variants and their impact on therapeutics and vaccines.

The paper presents the eQTL Catalogue, a resource containing uniformly processed eQTLs from 21 studies, enabling integrative analysis and identification of cell-type-specific eQTLs and disease colocalisations.

This study compares the epigenomes of neutrophils and monocytes to identify regulatory elements and chromatin states, revealing differences in enhancer activity and DNA methylation.

The paper describes the Ensembl Core software infrastructure for storing and accessing genome assemblies and annotations, supporting multiple species and providing APIs for programmatic access.