Author

Joost H.A. Martens

Radboud University NijmegenORCID 0000-0003-2008-6537Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Assay:DNA methylation· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Approach:experimental assay· 1

Frequent Co-Authors

Hendrik G. StunnenbergiD· 3 shared Kate DownesiD· 3 shared Mattia FrontiniiD· 3 shared Willem Hendrik OuwehandiD· 3 shared Dirk S. PauliD· 2 shared Frances BurdeniD· 2 shared Ivo Glynne GutiD· 2 shared Laura ClarkeiD· 2 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

Hendrik G. StunnenbergORCID

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4 papers

Recent·Most cited

Circulating immune signatures reveal targetable inflammatory pathways in anaplastic thyroid carcinoma

Pepijn van Houten, Titus Schlüter, Nicholas A. Sumpter, Prashant Changoer, Liesbeth van Emst, Leonie S. Helder, Julia I. P. van Heck, Joost H.A. Martens, Janneke E. W. Walraven, Petronella Beatrix Ottevanger, Han J. Bonenkamp, Johannes H.W. de Wilt, Mihai Netea, Martin Jaeger, Romana Netea-Maier

This study identifies systemic inflammation and proinflammatory cytokine profiles in anaplastic thyroid carcinoma, showing their role in tumor survival and suggesting therapeutic targeting.

bioRxiv · May 21, 2026 · PreprintCancer Biology

Cell type specific novel lincRNAs and circRNAs in the BLUEPRINT haematopoietic transcriptomes atlas.

Luigi Grassi, Osagie G. Izuogu, Natasha Andressa Nogueira Jorge, Denis Seyres, Mariona Bustamante, Frances Burden, Samantha Farrow, Neda Farahi, Fergal J. Martin, Adam Frankish, Jonathan M. Mudge, Myrto A. Kostadima, Romina Petersen, John J. Lambourne, Sophia Rowlston, , Mattia Frontini

The paper identifies novel long non-coding RNAs and circular RNAs in hematopoietic cells using BLUEPRINT consortium data, highlighting their cell type specificity.

bioRxiv · Sep 10, 2019 · PreprintGenomics

DNA methylation oscillation defines classes of enhancers

Emanuele Libertini, Rifat Hamoudi, Simon Charles Heath, Lee Lancashire, Arcadio Rubio García, Luigi Grassi, Kate Downes, Willem Hendrik Ouwehand, Biola M. Javierre, Jonathan Cairns, Steven Wingett, Dirk S. Paul, Marta Gut, Ivo Glynne Gut, Joost H.A. Martens, , Stephan Beck

The paper identifies DNA methylation oscillations as a marker for enhancer classification, showing high predictive power compared to other methods.

bioRxiv · Oct 10, 2018 · PreprintGenomics

Comparative analysis of neutrophil and monocyte epigenomes

Daniel Rico, Joost H.A. Martens, Kate Downes, Enrique Carrillo de Santa Pau, Véra Pancaldi, Alessandra Breschi, David Richardson, Simon Charles Heath, Sadia Saeed, Mattia Frontini, Lu Chen, Stephen B. Watt, Fabian Müller, Laura Clarke, Hindrik H. D. Kerstens, , Hendrik G. Stunnenberg

This study compares the epigenomes of neutrophils and monocytes to identify regulatory elements and chromatin states, revealing differences in enhancer activity and DNA methylation.

bioRxiv · Dec 22, 2017 · PreprintGenomics