Author

Caroline J. Sheeba

Imperial College LondonORCID 0000-0001-5357-4743Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:DNA methylation· 2 Approach:experimental assay· 2 Organism:C. elegans· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Organism:E. coli· 1

Frequent Co-Authors

Peter SarkiesiD· 2 shared Anke KonradiD· 1 shared Joanna KrwawicziD· 1 shared Katie Hains· 1 shared Skirmantas KriaučionisiD· 1 shared Terry C. McMahoniD· 1 shared Toni BeltraniD· 1 shared Tony BélicardiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMolecular Biology

Peter SarkiesORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Introduction of cytosine-5 DNA methylation sensitizes cells to oxidative damage

Joanna Krwawicz, Caroline J. Sheeba, Katie Hains, Terry C. McMahon, Yimo Zhang, Skirmantas Kriaučionis, Peter Sarkies

This study shows that introducing 5mC into E. coli increases sensitivity to oxidative stress and alkylating agents due to reactive oxygen species and DNA damage.

bioRxiv · Sep 13, 2024 · PreprintMolecular Biology

Long-term experimental evolution reveals purifying selection on piRNA-mediated control of transposable element expression

Ulfar Bergthorsson, Caroline J. Sheeba, Anke Konrad, Tony Bélicard, Toni Beltran, Vaishali Katju, Peter Sarkies

This study shows that natural selection in C. elegans maintains low TE expression, with increased TE expression observed in smaller populations due to reduced silencing efficiency.

BMC Biology · Nov 6, 2020Peer-reviewedMolecular Biology