Marin L. Gantner

This study shows NT-501 reduces photoreceptor death in retinal models by CNTF-dependent JAK/STAT3 activation, establishing an optimal dose range for efficacy.

This study identifies serine dehydratase (Sds) as a regulator of serine and sphingolipid metabolism, showing that its deletion improves skin repair in diabetic mice.

Signaling Pathways Project maps over 10,000 transcriptomic and ChIP-Seq experiments to signaling nodes and ranks node targets by meta-analysis (consensomes), validated against literature and bench assays.