Author

Aurélie Laguerre

Salk Institute for Biological StudiesORCID 0000-0002-8167-3586Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Christian M. MetalloiD· 3 shared Emeline JouliaiD· 2 shared Adrian M. WongiD· 1 shared Annalise BondiD· 1 shared Citlalic Arechiga· 1 shared David A. BrenneriD· 1 shared Emily M.J. Fennell· 1 shared Ethan L. AshleyiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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3 shared papersImmunology

Christian M. MetalloORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

IL-10/ACOD1 axis regulates catabolism of phagocytosed lipids in trained macrophages

Mack B. Reynolds, Annalise Bond, Emily M.J. Fennell, Kym J. Grae, Emeline Joulia, Matthew P. Donnelly, Melissa A. Johnson, Aurélie Laguerre, Gladys R. Rojas, Matthew J. Kolar, Janelle S. Ayres, Christian M. Metallo, Gerald S. Shadel

This study identifies an IL-10/ACOD1 axis that reprograms lipid metabolism in trained macrophages to promote resolution of inflammation.

bioRxiv · Aug 23, 2026 · PreprintImmunology

1-Deoxysphingolipids dysregulate membrane properties and cargo trafficking in the early secretory pathway

Yi-Ting Tsai, Nicolas-Frédéric Lipp, Olivia Seidel, Riya Varma, Aurélie Laguerre, Kristina Solorio-Kirpichyan, Adrian M. Wong, Roberto J. Brea, Grace H. McGregor, Thekla Cordes, Neal K. Devaraj, Lars Kuerschner, Sonya E. Neal, Christian M. Metallo, Itay Budin

This study investigates how 1-deoxysphingolipids affect membrane properties and cargo trafficking in the early secretory pathway by analyzing their subcellular distribution and effects on ER membrane fluidity and ERES.

Cell chemical biology · Jan 1, 2026Peer-reviewedCell Biology

Targeting serine dehydratase supports amino acid homeostasis and skin repair

Emeline Joulia, Ethan L. Ashley, Patrick Tseng, Citlalic Arechiga, Yuqiong Liang, Aurélie Laguerre, Maureen L. Ruchhoeft, Joseph Rainaldi, Michal K. Handzlik, Regis J. Fallon, Hyun Young Kim, Prashant Mali, David A. Brenner, Tatiana Kisseleva, Ye Zheng, , Christian M. Metallo

This study identifies serine dehydratase (Sds) as a regulator of serine and sphingolipid metabolism, showing that its deletion improves skin repair in diabetic mice.

bioRxiv · Oct 23, 2025 · PreprintPhysiology