Molecular BiologybioRxivPreprint
Ablation of telomerase reverse transcriptase in Leishmania major results in a senescent-like phenotype and loss of infectivity
Mark Ewusi Shiburah, Beatriz C. D. de Oliveira, Habtye Bisetegn…·Maria Isabel Nogueira Cano
This study shows that deleting TERT in Leishmania major causes senescent-like traits and reduced infectivity, suggesting it as a potential drug target.
DOI 10.1101/2023.11.10.566596