Author

Maria Isabel Nogueira Cano

Universidade Estadual Paulista (Unesp)ORCID 0000-0001-9798-6627Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2

Frequent Co-Authors

Adriano C. CoelhoiD· 2 shared Beatriz C. D. de OliveiraiD· 2 shared Juliana Ide AokiiD· 2 shared Luiz H. C. AssisiD· 2 shared Mark Ewusi ShiburahiD· 2 shared Rubem F. S. Menna‐BarretoiD· 2 shared Benedito Donizete MenozziiD· 1 shared Débora Andrade-SilvaiD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Adriano C. CoelhoORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintNov 10, 2023

The impact of knocking out the Leishmania major telomerase RNA (LeishTER): from altered cell proliferation to decreased parasite infectivity

Beatriz C. D. de Oliveira, Mark Ewusi Shiburah, Luiz H. C. Assis…·Maria Isabel Nogueira Cano

This study investigates the role of Leishmania major telomerase RNA (LeishTER) by generating knockout parasites, showing reduced proliferation, telomere shortening, and decreased infectivity.

DOI 10.1101/2023.11.10.566567

experimental assay

𝕏 PostBluesky

Molecular BiologybioRxivPreprintNov 10, 2023

Ablation of telomerase reverse transcriptase in Leishmania major results in a senescent-like phenotype and loss of infectivity

Mark Ewusi Shiburah, Beatriz C. D. de Oliveira, Habtye Bisetegn…·Maria Isabel Nogueira Cano

This study shows that deleting TERT in Leishmania major causes senescent-like traits and reduced infectivity, suggesting it as a potential drug target.

DOI 10.1101/2023.11.10.566596

experimental assay

𝕏 PostBluesky