Author

Itamar Menuhin-Gruman

Tel Aviv UniversityORCID 0000-0001-5394-6949Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:CRISPR screen· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1 Organism:plant (other)· 1 Research Focus:software / tool· 1 Approach:statistical model· 1

Frequent Co-Authors

Shaked BergmaniD· 2 shared Tamir TulleriD· 2 shared Adi Yahalom· 1 shared Alina Wiener· 1 shared Amir SagiiD· 1 shared Anat Lavi-Itzkovitz· 1 shared Anat Maoz· 1 shared Anna RiceiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersSynthetic Biology

Shaked BergmanORCID

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2 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintMar 18, 2026

Context-dependent determinants of CRISPR-Cas9 editing efficiency revealed through cross-species endogenous editing analysis

Shai Cohen, Shaked Bergman, Adi Yahalom…·Tamir Tuller

The paper identifies context-dependent factors affecting CRISPR-Cas9 editing efficiency across species using endogenous editing data and shows that repair outcomes are conserved.

DOI 10.64898/2026.03.18.712093

humanmouse

𝕏 PostBluesky

Synthetic BiologyScience AdvancesPeer-reviewedOct 1, 2025

AI-directed gene fusing prolongs the evolutionary half-life of synthetic gene circuits

Itamar Menuhin-Gruman, Matan Arbel, Doron Naki…·Tamir Tuller

The paper introduces a gene fusion strategy using machine learning to improve the evolutionary stability of synthetic gene circuits in yeast.

4 citations

yeastmachine learning (classical)

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