Author

Yiming Wan

Stony Brook UniversityORCID 0000-0001-5466-3895Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:non-human primate· 1 Research Focus:perturbation response prediction· 1

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Christopher HelenekiD· 1 shared Damiano Coraci· 1 shared Gábor BalázsiiD· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperSynthetic Biology

Christopher HelenekORCID

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1 paper

Recent·Most cited

Synthetic BiologyACS Synthetic BiologyPeer-reviewedOct 8, 2024

Optimizing a CRISPR-Cas13d gene circuit for tunable target RNA downregulation with minimal collateral RNA cutting

Yiming Wan, Christopher Helenek, Damiano Coraci, Gábor Balázsi

This paper develops MONARCH gene circuits to optimize CRISPR-Cas13d for tunable RNA downregulation with minimal off-target effects in human and green monkey cells.

5 citations

humannon-human primate

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