Author

Rui F. O. Silva

Erasmus MCORCID 0000-0001-5470-778XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:imaging· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:software / tool· 1 Approach:statistical model· 1 Organism:zebrafish· 1

Frequent Co-Authors

Brígida R. PinhoiD· 1 shared Bruno SousaiD· 1 shared Daan BrinksiD· 1 shared Hunor Bartalis-SzelyesiD· 1 shared Jorge M. A. OliveiraiD· 1 shared José BessaiD· 1 shared Leonor Pereira LimaiD· 1 shared Liliana M. AlmeidaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperPharmacology & Toxicology

Brígida R. PinhoORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologyPharmacological ReportsPeer-reviewedFeb 13, 2026

PERK inhibition with GSK2606414 in zebrafish evokes developmental defects consistent with Wolcott-Rallison syndrome phenotypes

Liliana M. Almeida, Leonor Pereira Lima, Nuno A. S. Oliveira…·Jorge M. A. Oliveira

This study uses zebrafish to model Wolcott-Rallison syndrome by inhibiting PERK with GSK2606414, revealing developmental defects consistent with the syndrome.

DOI 10.1007/s43440-026-00837-7

zebrafishimaging

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NeurosciencebioRxivPreprintSep 26, 2025

Robustness and fidelity of voltage imaging analysis pipelines

Rui F. O. Silva, Hunor Bartalis-Szelyes, Daan Brinks, Zhenyu Gao

This study evaluates voltage imaging analysis pipelines, identifies their strengths and limitations, and proposes a decision-tree for selecting appropriate analysis strategies based on experimental conditions.

DOI 10.1101/2025.09.26.678573

imagingstatistical model

𝕏 PostBluesky