Author

Elizabeth A. Mueller

Howard Hughes Medical InstituteORCID 0000-0001-5482-6551Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Christine JacobsiD· 2 shared Joshua W. McCauslandiD· 2 shared Allen C. SteereiD· 1 shared Catherine Leimkuhler GrimesiD· 1 shared Constantin N. TakacsiD· 1 shared Irnov IrnoviD· 1 shared Jeline Buron· 1 shared Jenny WachteriD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMicrobiology

Christine JacobsORCID

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2 papers

Recent·Most cited

MicrobiologyJournal of BacteriologyPeer-reviewedFeb 14, 2025

Borrelia burgdorferi loses essential genetic elements and cell proliferative potential during stationary phase in culture but not in the tick vector.

Jessica Zhang, Constantin N. Takacs, Joshua W. McCausland…·Christine Jacobs

This paper shows that Borrelia burgdorferi loses genetic elements and proliferative ability in lab cultures during starvation but maintains these traits in tick vectors.

4 citations

bacteria (other)whole-genome sequencing

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MicrobiologybioRxivPreprintJan 8, 2025

Bacterial and host enzymes modulate the inflammatory response produced by the peptidoglycan of the Lyme disease agent

Joshua W. McCausland, Zachary A. Kloos, Irnov Irnov…·Christine Jacobs

This study identifies bacterial enzymes that modify peptidoglycan fragments from Borrelia burgdorferi, showing they are poor immune stimulators and that host enzymes like PGLYRP2 are less active in joint fluids, contributing to persistent arthritis.

3 citations

humanproteomics

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