Author

Huahua Jian

Shanghai Jiao Tong UniversityORCID 0000-0001-5507-497XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:ecology & biodiversity· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1

Frequent Co-Authors

Chang NieiD· 1 shared Chengpeng Li· 1 shared Fabai WuiD· 1 shared Fengmin XingiD· 1 shared Fengping WangiD· 1 shared Jiaxue Peng· 1 shared Jing LiaoiD· 1 shared Keith Dufault‐ThompsoniD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperSystems Biology

Chang NieORCID

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2 papers

Recent·Most cited

MicrobiologyNature CommunicationsPeer-reviewedJan 8, 2026

Co-occurrence of diverse defense systems shapes complex microbe-virus relationships in deep-sea cold seeps

Yingchun Han, Jing Liao, Chengpeng Li…·Xiyang Dong

The paper analyzes defense and anti-defense systems in microbes and viruses from cold seeps, revealing co-occurrence and coevolution of these systems across diverse microbial lineages.

3 citations

metagenomicsexperimental assay

𝕏 PostBluesky

Systems BiologymSystemsPeer-reviewedAug 11, 2022

Reconstruction and analysis of thermodynamically-constrained models reveal metabolic responses of a deep-sea bacterium to temperature perturbations

Keith Dufault‐Thompson, Chang Nie, Huahua Jian…·Ying Zhang

This study uses thermodynamically-constrained genome-scale models to simulate metabolic responses of a deep-sea bacterium to different temperatures, revealing changes in metabolic efficiency and pathway utilization.

6 citations

bacteria (other)whole-genome sequencing

𝕏 PostBluesky