Yingchun Han

This paper introduces AMPHORA, a pathogen-conditioned generator of antimicrobial peptides, showing that incorporating pathogen-specific features improves peptide design and potency.

The paper constructs a global virome atlas of cold seep ecosystems, revealing novel viral diversity and biotechnological potential.

This study reveals a distinct microbial-viral biome in sandy beaches, structured by tidal zonation, with high genomic novelty and metabolic shifts across cross-shore gradients.

The paper analyzes defense and anti-defense systems in microbes and viruses from cold seeps, revealing co-occurrence and coevolution of these systems across diverse microbial lineages.

The paper constructs a deep-sea small protein atlas, identifies noncanonical antimicrobial peptides, and demonstrates their antimicrobial efficacy and non-lytic mechanisms.

This study shows that seabed ecosystems rapidly collapse and form a methane biofilter after methane leakage from hydrates, with significant microbial and macrofaunal changes.

This study identifies and characterizes quorum sensing systems in deep-sea cold seep microbial communities, revealing their role in regulating biogeochemical processes.

The paper investigates reductive dehalogenation in deep-sea cold seeps, identifying diverse RDases and their ecological role in biogeochemical cycles.

This study analyzes the virulome and resistome of deep-sea cold seeps, finding minimal public health risks due to low abundance of high-risk genes and non-pathogenic functions.

This study identifies cold seeps as significant nitrogen-loss hotspots, revealing diverse microbial communities and active nitrogen-loss genes across multiple phyla.

This study tracks microbial succession, community assembly, and adaptation over five years at a deep-sea cold seep, revealing shifts in community structure and functional adaptations.

This study analyzes viral communities in marine biofilms on 8 materials to explore their roles in microbially influenced corrosion, finding viruses influence corrosion through interactions with corrosive microbes.