Elien Vandermarliere

The paper analyzes phospho-proteomics data to characterize phosphorylation sites, showing phosphorylated residues are more flexible and disease-linked mutations in rigid regions are more prevalent.

The paper develops SECRiFY, a method to assess secretability of protein fragments in yeast, revealing intrinsic disorder and flexibility as key factors.

The paper evaluates integrating Percolator into COSS for improved peptide identification sensitivity and specificity using multiple datasets and search tools.

Scop3P provides a comprehensive database of human phosphosites with structural and biophysical context, integrating sequence, structure, and phosphoproteomics data.

COSS is a spectral library search tool that identifies more peptides faster than existing tools and supports multiple data formats.