Fotis Tsetsos

This study performs a single-nucleus transcriptome-wide association study to identify gene-trait associations in brain disorders, revealing cell-type-specific genetic regulation and ancestry-specific patterns.

The paper constructs a single-nucleus atlas of genetic regulation in the human brain, identifying cell-type-specific regulatory effects and disease-associated genes.

The paper constructs a single-cell transcriptomic atlas of the human dorsolateral prefrontal cortex across neurodegenerative and neuropsychiatric diseases, revealing shared and distinct molecular mechanisms.

The paper presents long-read assemblies of 43 diverse human Y chromosomes, revealing extensive structural complexity and variation across 180,000 years of evolution.

This study identifies two novel genetic loci associated with Tourette Syndrome through a genome-wide meta-analysis and integrates functional data to implicate specific genes.

This study identifies gene sets associated with Tourette Syndrome using genome-wide data, highlighting synaptic and immune-related pathways.

This study performs a cross-disorder GWAS meta-analysis of ADHD, ASD, OCD, and TS, identifying 297 genome-wide significant variants and 21 genes associated with shared genetic risk.

The paper identifies two rare copy number variants, NRXN1 and CNTN6, significantly increasing the risk of Tourette syndrome in a European ancestry sample.