Cell BiologybioRxivPreprint
Diet induced insulin resistance is due to induction of PTEN expression
Radha Mukherjee, Priya Pancholi, Malvika Sharma…·Neal X. Rosen
The paper shows that diet-induced insulin resistance results from increased PTEN expression, which inhibits PI3K signaling, and that PTEN and mTORC1 inhibitors can reverse this effect.
2 citations