Michael J. McGeachie

The paper identifies cell types regulated by circulating miRNAs linked to asthma exacerbations using scRNA-seq and validates findings in GEO datasets.

The paper identifies DNA-methylation markers at birth and childhood associated with lung function and reveals sex- and genetics-related pathways linked to asthma and lung development.

This paper introduces GENN, a method for multi-omic interactome analysis that improves prediction of biomedical outcomes by learning salient associations in a low-dimensional space.

The paper introduces miRAIDD, a database of human miRNA-disease causal associations generated using large language models, and quantifies miRNA pleiotropy and its biological characteristics.

The paper develops OMICmAge, a multi-omics biomarker of biological age, and shows it outperforms existing markers in predicting chronic diseases and mortality.